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CIO Sahm Adrangi Explains His Negative Views On Proteostasis Therapeutics

April 23, 2018 • divinefuel

Kerrisdale Capital Management’s Sahm Adrangi issued a report in support of his decision to short the stock of Proteostasis Therapeutics, Inc. This is a biopharmaceutical firm who has a drug in development called PTI-428. The value of this company largely depends on the success of this one drug which is being clinically studied to treat cystic fibrosis. Their stock doubled when the FDA designated PTI-428 as both a Breakthrough Therapy and as an Orphan Drug. However, the analysts working for Sahm Adrangi say that this drug is in all likelihood ineffective and will never be released.

There are two main problems with PTI-428, Sahm Adrangi says. The first is that his analysts have shown that the pattern of data for this candidate drug is of low quality. Secondly, he says that Proteostasis Therapeutics has been omitting some critical information in their public disclosures. He said this company released their Phase 2 clinical trial results in December 2017 which claimed that PTI-428 showed improved lung function over the results of a placebo.

However, Sahm Adrangi says that once his analysts dug into the details they saw that these Phase 2 results are not nearly as meaningful as investors have been led to believe. He said the drug didn’t actually improve patient’s health, it was that the four patients who had taken placeboes did very poorly which made PTI-428 look a lot more effective than it actually is. Phase 1 had shown the PTI-428 didn’t improve lung function in any meaningful way and in reality that was what Phase 2 confirmed. Later in the day after he issued his report Sahm Adrangi had held a teleconference in order to further explain his negative position on Proteostasis Therapeutics.

After graduating from Yale University with a bachelor of arts in economics, Sahm Adrangi found his first position at Deutsche Bank. He went on to work for two other investment firms before founding Kerrisdale Capital Management and starting his own hedge fund. He says his personal investment style is value. His company now manages $300 million which is mostly in long-term value investments. The rest is shorting the stocks of companies that he sees as overvalued.

http://www.valuewalk.com/2017/11/sahm-adrangi-kerrisdale-capital-luxoft/

Bob Reina, CEO OF Talk Fusion offers Tips on Effective Video Marketing

November 15, 2017 • divinefuel

Talk Fusion, based in Florida, is a global leader in the provision of video marketing solutions. Founder and CEO, Bob Reina, established the all-in-one stop for video marketing services in 2007. The firm creates a platform with various ways of marketing that are more engaging and persuasive and guarantee results.

 

Talk Fusion has shown commitment to assisting businesses to withstand competition by being innovative in marketing and increasing sales and profits. The firm’s services are marketed from person to person and provided by independent associates in over 140 countries. Talk Fusion allows consumers a 30-day free trial period for them to try out the product before considering a purchase. The firm, as well as the CEO, is also passionate about giving back to the community by donating to various charity organizations globally. Reina boasts of over 25 years of experience in video marketing and direct sales.

 

In April 2017, news provider, The Huffington Post changed the name to HuffPost. Mr. Bob Reina published new articles coinciding with the rebranding of the news provider. Reina has, however, been a contributor to the HuffPost since August 2006. During this period, he has offered insight into the trends in the video marketing industry while also helping individuals with entrepreneurial, self-development and lifestyle skills possibly reaching HuffPost’s over 200 million readers.

 

Reina insists on the essence of understanding your audience to deliver your message to the right group. One needs to research the target market to develop focused marketing campaigns. Focus on the problems that your product aims to solve and market the product with the fictionalized buyer in mind. This will resonate with many potential buyers rather than addressing all buyers in general.

 

Research on your competition to know what they are doing differently and whether they are excelling or not. You can also check on social media to identify the likes and preferences of customers. Analytics tools can also be of great help in determining what works best and what customers like. Researching your market and learning the tiny details will enable you to know how to relay your content when marketing and even which words to use. Learn more: https://www.linkedin.com/company/talk-fusion-corporate

 

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